02922nam a22003857a 4500 SNU 20160926140407.0 160413b xxu||||| |||| 00| 0 eng d 9780123820303 Global Information Systems Technology Pvt Ltd 877, Udhyog Vihar, Phase-V, Gurgaon 615.1 SIL Silverman, Richard B., The organic chemistry of drug design and drug action. Third edition / Amsterdam ; Academic Press, an imprint of Elsevier, ©2014 xviii, 517 pages : illustrations ; 24 cm. Chapter 1 - Introduction, In The Organic Chemistry of Drug Design and Drug Action http://www.sciencedirect.com/science/article/pii/B9780123820303000015 Chapter 2 - Lead Discovery and Lead Modification, http://www.sciencedirect.com/science/article/pii/B9780123820303000027 Chapter 3 - Receptors, In The Organic Chemistry of Drug Design and Drug Action http://www.sciencedirect.com/science/article/pii/B9780123820303000039 Chapter 4 - Enzymes, In The Organic Chemistry of Drug Design and Drug Action http://www.sciencedirect.com/science/article/pii/B9780123820303000040 Chapter 5 - Enzyme Inhibition and Inactivation, http://www.sciencedirect.com/science/article/pii/B9780123820303000052 Chapter 6 - DNA-Interactive Agents, http://www.sciencedirect.com/science/article/pii/B9780123820303000064 Chapter 7 - Drug Resistance and Drug Synergism, http://www.sciencedirect.com/science/article/pii/B9780123820303000076 Chapter 8 - Drug Metabolism, http://www.sciencedirect.com/science/article/pii/B9780123820303000088 Chapter 9 - Prodrugs and Drug Delivery Systems, http://www.sciencedirect.com/science/article/pii/B978012382030300009X Abstract : Provides a basis and overall context for concepts introduced and discussed in more detail in subsequent chapters in this book. An historical context is given to the topic of drug discovery, followed by a high level overview of modern approaches to rational drug design. The approaches and steps typically encountered in modern rational drug design, including target identification, lead discovery, and lead modification, are introduced, and an overview of the subsequent steps required for drug development prior to regulatory approval, such as pharmacokinetics, preclinical studies, clinical trials, and intellectual property issues, are summarized. http://www.sciencedirect.com/science/book/9780124186910 Bioorganic chemistry. Pharmaceutical chemistry. Molecular pharmacology. Drugs Design. E-Books Holladay, Mark W., E-Book http://www.sciencedirect.com/science/book/9780123820303 ddc ER 46931 46931 0 0 ddc Document, Internet resource 0 1 REF SNUL SNUL 2016-09-26 Science Direct®, (Elsevier) 10500.00 0 615.1 SIL ER40 2016-09-26 00:00:00 2016-09-26 ER