TY - BOOK AU - Brittain , Harry G AU - Brittain, Harry G TI - Polymorphism in Pharmaceutical Solids T2 - Drugs and the pharmaceutical sciences, v. 192 SN - 9780367193317 U1 - 615.19 BRI PY - 1999/// CY - New York PB - : M. Dekker, KW - Medicine KW - Medicine and health KW - Pharmacology and therapeutics KW - Polymorphism Crystallography KW - Crystallization KW - Hydration KW - Aufsatzsammlung KW - Molecular Structure KW - Médicaments -- Dissolution N1 - heory and principles of polymorphic systems / Harry G. Brittain -- Application of the phase rule to the characterization of polymorphic and solvatomorphic systems / Harry G. Brittain -- Computational methodologies : towards crystal structure and polymorph prediction / Sarah (Sally) L. Price -- Classical methods of preparation of polymorphs and alternative solid forms / Peter W. Cains -- Approaches to high-throughput physical form screening and discovery / Alastair J. Florence -- Structural aspects of polymorphism / Harry G. Brittain, Stephen R. Byrn, and Eunhee Lee -- Structural aspects of solvatomorphic systems / Harry G. Brittain, Kenneth R. Morris, and Stephan X.M. Boerrigter -- Pharmaceutical co-crystals : a new opportunity in pharmaceutical science for a long-known but little-studied class of compounds / Kapildev K. Arora and Michael J. Zaworotko -- Thermoanalytical and crystallographic methods / Sisir Bhattacharya, Harry G. Brittain, and Raj Suryanarayanan -- Vibrational spectroscopy / Harry G. Brittain -- Solid-state nuclear magnetic resonance spectroscopy / Patrick A. Tishmack -- Effects of polymorphism and solid-state solvation on solubility and dissolution rate / Harry G. Brittain, David J.R. Grant, and Paul B. Myrdal -- Solid-state phase transformations / Harry G. Brittain -- Effects of pharmaceutical processing on the solid form of drug and excipient materials / Peter L.D. Wildfong -- Structural aspects of molecular dissymmetry / Harry G. Brittain -- Amorphous solids / Lynne S. Taylor and Sheri L. Shamblin N2 - Using clear and practical examples, Polymorphism in Pharmaceutical Solids, Second Edition presents a complete examination of polymorphic behavior in pharmaceutical development ER -