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  <titleInfo>
    <title>Systems Medicine</title>
    <subTitle>: Physiological Circuits and the Dynamics of Disease</subTitle>
  </titleInfo>
  <name type="personal">
    <namePart>Alon, Uri.</namePart>
    <role>
      <roleTerm authority="marcrelator" type="text">creator</roleTerm>
    </role>
  </name>
  <name type="personal">
    <namePart>Uri Alon.</namePart>
  </name>
  <typeOfResource>text</typeOfResource>
  <originInfo>
    <place>
      <placeTerm type="text">New York</placeTerm>
    </place>
    <publisher>: CRC Press</publisher>
    <dateIssued>, 2024</dateIssued>
    <issuance>monographic</issuance>
  </originInfo>
  <language>
    <languageTerm authority="iso639-2b" type="code">eng</languageTerm>
  </language>
  <physicalDescription>
    <form authority="marcform">print</form>
    <extent>xi,255p. : 24cm.</extent>
  </physicalDescription>
  <abstract>Why do we get certain diseases, whereas other diseases do not exist?

In this book, Alon, one of the founders of systems biology, builds a foundation for systems medicine.

Starting from basic laws, the book derives why physiological circuits are built the way they are. The circuits have fragilities that explain specific diseases and offer new strategies to treat them.

By the end, the reader will be able to use simple and powerful mathematical models to describe physiological circuits. The book explores, in three parts, hormone circuits, immune circuits, and aging and age-related disease. It culminates in a periodic table of diseases.

Alon writes in a style accessible to a broad range of readers - undergraduates, graduates, or researchers from computational or biological backgrounds. The level of math is friendly and the math can even be bypassed altogether. For instructors and readers who want to go deeper, the book includes dozens of exercises that have been rigorously tested in the classroom.

</abstract>
  <note type="statement of responsibility">/ Uri Alon.</note>
  <subject>
    <topic>Medicine</topic>
  </subject>
  <subject>
    <topic>Dynamics of Disease</topic>
  </subject>
  <subject>
    <topic>Biology</topic>
  </subject>
  <classification authority="ddc">610.72 ALO</classification>
  <identifier type="isbn">9781032411859</identifier>
  <identifier type="">: Zafaa Books &amp; Distributors : 313/56F, 49A, Anand Nagar, Inderlok, Delhi</identifier>
  <recordInfo>
    <recordCreationDate encoding="marc">240215</recordCreationDate>
    <recordChangeDate encoding="iso8601">20240402124355.0</recordChangeDate>
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