000			02922nam a22003857a 4500
003			SNU
005			20160926140407.0
008			160413b xxu||||| |||| 00| 0 eng d
020			_a9780123820303
028			_aGlobal Information Systems Technology Pvt Ltd _b877, Udhyog Vihar, Phase-V, Gurgaon
082			_a615.1 SIL
100			_aSilverman, Richard B.,
245			_aThe organic chemistry of drug design and drug action. _bThird edition /
260			_aAmsterdam ; _bAcademic Press, an imprint of Elsevier, _c©2014
300			_axviii, 517 pages : _billustrations ; _c24 cm.
505			_aChapter 1 - Introduction, In The Organic Chemistry of Drug Design and Drug Action _uhttp://www.sciencedirect.com/science/article/pii/B9780123820303000015
505			_aChapter 2 - Lead Discovery and Lead Modification, _uhttp://www.sciencedirect.com/science/article/pii/B9780123820303000027
505			_aChapter 3 - Receptors, In The Organic Chemistry of Drug Design and Drug Action _uhttp://www.sciencedirect.com/science/article/pii/B9780123820303000039
505			_aChapter 4 - Enzymes, In The Organic Chemistry of Drug Design and Drug Action _uhttp://www.sciencedirect.com/science/article/pii/B9780123820303000040
505			_aChapter 5 - Enzyme Inhibition and Inactivation, _uhttp://www.sciencedirect.com/science/article/pii/B9780123820303000052
505			_aChapter 6 - DNA-Interactive Agents, _uhttp://www.sciencedirect.com/science/article/pii/B9780123820303000064
505			_aChapter 7 - Drug Resistance and Drug Synergism, _uhttp://www.sciencedirect.com/science/article/pii/B9780123820303000076
505			_aChapter 8 - Drug Metabolism, _uhttp://www.sciencedirect.com/science/article/pii/B9780123820303000088
505			_aChapter 9 - Prodrugs and Drug Delivery Systems, _uhttp://www.sciencedirect.com/science/article/pii/B978012382030300009X
520			_aAbstract : Provides a basis and overall context for concepts introduced and discussed in more detail in subsequent chapters in this book. An historical context is given to the topic of drug discovery, followed by a high level overview of modern approaches to rational drug design. The approaches and steps typically encountered in modern rational drug design, including target identification, lead discovery, and lead modification, are introduced, and an overview of the subsequent steps required for drug development prior to regulatory approval, such as pharmacokinetics, preclinical studies, clinical trials, and intellectual property issues, are summarized. _uhttp://www.sciencedirect.com/science/book/9780124186910
650			_aBioorganic chemistry. _2
650			_aPharmaceutical chemistry.
650			_aMolecular pharmacology.
650			_aDrugs
650			_aDesign.
650			_aE-Books
700			_aHolladay, Mark W.,
856			_3E-Book _uhttp://www.sciencedirect.com/science/book/9780123820303
942			_2ddc _cER
999			_c46931 _d46931