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020 _a9789048125814
028 _a: International Book Distributor
_b: Flat No.- 17, Prakash Apartment, Ansari Road, New Delhi- 110002
_c: 118484
_d: 14/11/2022
082 _a547.7 CRA
100 _aCragg, Peter J.
245 _aSupramolecular chemistry
_b : from biological inspiration to biomedical applications.
_c/ Peter J. Cragg.
260 _a, Dordrecht
_b: Springer
_c, 2010.
300 _axv,260p.
_c: 26cm.
365 _b10841
520 _aSupramolecular chemistry is often described as the study of chemistry beyond the simple molecular level yet it is often forgotten how many of the pioneering su-pramolecular chemists looked to molecular biology for their ideas. The search for an aldolase enzyme mimic, the discovery of crown ethers that transported potas-sium as efficiently as valinomycin, and the synthesis of an antitubercular com-pound that resembled a transmembrane protein, all point to a biological inspira-tion. Since the field emerged in the last quarter of the 20th Century, advances in the synthesis of multifunctional molecules, coupled to a greater understanding of biological processes at the molecular level, have led supramolecular chemists to design compounds that not only mimic those in Nature but also have diagnostic and therapeutic applications. The book opens with an overview of supramolecular chemistry. In subsequent chapters parallels are drawn with biological phenomena: the formation of proteins and other biomolecules, the evolution of cells, and the design of channel-forming molecules and enzymes. The application of supramolecular principles to sensors and magic bullet therapies is explained and the future of supramolecular therapeutics is considered. The exciting combination of supramolecular chemistry and nanotechnology is discussed together with the likelihood that nanoengineered smart materials could one day circulate in the body to treat patients before they became aware of any symptoms. Supramolecular Chemistry: From Biological Inspiration to Biomedical Applications is aimed at postgraduates working at the chemistry/life science interface and final year undergraduate advanced options in supramolecular chemistry. It is hoped that it will also be of value to academics and professionals interested in the relevance of supramolecular chemistry to biology and vice versa.
650 _aChimie supramoléculaire
650 _aScience des matériaux
650 _aSupramolecular chemistry
650 _aCragg, Peter J.
700 _aPeter J. Cragg.
942 _cBOOK
999 _c59777
_d59777