The organic chemistry of drug design and drug action.

Silverman, Richard B.,

The organic chemistry of drug design and drug action. Third edition / - Amsterdam ; Academic Press, an imprint of Elsevier, ©2014 - xviii, 517 pages : illustrations ; 24 cm.

Chapter 1 - Introduction, In The Organic Chemistry of Drug Design and Drug Action http://www.sciencedirect.com/science/article/pii/B9780123820303000015 Chapter 2 - Lead Discovery and Lead Modification, http://www.sciencedirect.com/science/article/pii/B9780123820303000027 Chapter 3 - Receptors, In The Organic Chemistry of Drug Design and Drug Action http://www.sciencedirect.com/science/article/pii/B9780123820303000039 Chapter 4 - Enzymes, In The Organic Chemistry of Drug Design and Drug Action http://www.sciencedirect.com/science/article/pii/B9780123820303000040 Chapter 5 - Enzyme Inhibition and Inactivation, http://www.sciencedirect.com/science/article/pii/B9780123820303000052 Chapter 6 - DNA-Interactive Agents, http://www.sciencedirect.com/science/article/pii/B9780123820303000064 Chapter 7 - Drug Resistance and Drug Synergism, http://www.sciencedirect.com/science/article/pii/B9780123820303000076 Chapter 8 - Drug Metabolism, http://www.sciencedirect.com/science/article/pii/B9780123820303000088 Chapter 9 - Prodrugs and Drug Delivery Systems, http://www.sciencedirect.com/science/article/pii/B978012382030300009X

Abstract : Provides a basis and overall context for concepts introduced and discussed in more detail in subsequent chapters in this book. An historical context is given to the topic of drug discovery, followed by a high level overview of modern approaches to rational drug design. The approaches and steps typically encountered in modern rational drug design, including target identification, lead discovery, and lead modification, are introduced, and an overview of the subsequent steps required for drug development prior to regulatory approval, such as pharmacokinetics, preclinical studies, clinical trials, and intellectual property issues, are summarized. http://www.sciencedirect.com/science/book/9780124186910

9780123820303

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Bioorganic chemistry.
Pharmaceutical chemistry.
Molecular pharmacology.
Drugs
Design.
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