Biomedical Applications of Microfluidic Devices

Hamblin, Michael R Karimi, Mahdi

Biomedical Applications of Microfluidic Devices / Michael R Hamblin - Amsterdam : Academic Press, 2021 - xviii, 332p. 24cm.

Intro --
Biomedical Applications of Microfluidic Devices --
Copyright --
Dedication --
Contents --
Contributors --
Preface --
Chapter 1 An overview of microfluidic devices --
1.1 Introduction --
1.2 Chemical synthesis --
1.3 Drug delivery --
1.4 Cell biology --
1.5 Biosensors --
References --
Chapter 2 Microfluidic devices: Synthetic approaches --
2 Cleanroom --
2.1 Classification --
2.2 Cleanroom concepts --
2.3 Cleanroom equipment --
2.4 Materials --
2.4.1 Polydimethylsiloxane --
2.4.2 SU-8 --
2.4.3 Silicon --
2.4.4 Glass --
2.4.5 Nonmetal thin films --
2.4.6 Metals 2.5 Deposition methods --
2.5.1 Deposition methods for Si 3 N 4 and SiO 2 --
2.5.2 Deposition methods for thin metal layers --
2.5.3 Deposition methods for thick metal layers --
2.6 Lithography --
2.6.1 Photolithography --
2.7 Etching techniques --
2.7.1 Features of etching procedures --
2.7.2 Wet etching of thin films --
2.7.3 Isotropic wet etching of silicon and glass --
2.7.4 Anisotropic wet etching of silicon --
2.7.5 Dry etching methods --
2.8 Types of molding --
2.8.1 Soft lithography --
2.8.2 Injection molding --
2.8.3 Hot embossing --
2.9 3D printing --
2.10 Stereolithography 2.11 Fused deposition molding --
References --
Chapter 3 Microchannels for microfluidic systems --
3.1 Introduction --
3.2 Cross-section geometry in microchannels in microfluidic systems --
3.3 Channel design for different flow regimes (turbulent and laminar flow) --
3.4 Phase study in microfluidic devices and microchannel patterns --
3.5 Hydrodynamic behavior of the flow in microfluidic systems --
3.6 The velocity development in the microchannels --
3.7 Hydrophilicity and hydrophobicity effects in microfluidic systems --
3.8 Physical specifications of channels in microfluidic systems 3.8.1 Effect of friction coefficient of the microchannels in microfluidic devices --
3.8.2 Roughness effects in channels of microfluidic devices --
3.9 Biomedical applications of transport phenomena in microfluidic systems --
3.10 Pathogen detection by microchannel devices using nanotechnology --
3.11 Soft microchannels in biomedical applications --
3.12 Reusable microchannels in biomedical applications --
3.13 Conclusions --
References --
Chapter 4 Microarray technologies --
4.1 Introduction --
4.2 What are microarrays? --
4.2.1 DNA microarrays --
4.2.1.1 Fabrication methods for DNA microarrays 4.2.2 Protein microarrays --
4.2.2.1 Analytical protein microarrays --
4.2.2.2 Functional protein microarrays --
4.2.2.3 Reverse phase microarrays --
4.2.2.4 Fabrication of protein microarrays --
4.2.3 Cell microarrays --
4.3 Microfluidic arrays --
4.3.1 Advantages of microfluidic array technology --
4.3.2 Disadvantages of microfluidic array technology --
4.3.3 Fabrication of microfluidic arrays --
4.3.4 Automated microfluidic arrays (lab-on-a-chip systems) --
4.3.5 Examples of microfluidic arrays --
4.4 Conclusion --
References --
Chapter 5 Microfluidics: Organ-on-a-chip

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Technology
Medicine and health
Medical instruments and apparatus.
Microfluidic devices.
Microfluidics.

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